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NEUROMUSCULAR DISORDERS

IVIG Therapy

Specific neuromuscular disorders such as chronic inflammatory demyelinating polyneuropathy (CIDP) and Guillain-Barré Syndrome (GBS) can be treated with steroids, plasmapheresis (PP) and immunosuppressive drugs.  Many patients initially respond to these treatments, but develop resistance to the therapy or experience side effects causing the treatments to be stopped.

Tolerability

Tolerability of IVIG is usually very good and adverse reactions are usually minor. The most common side effects are headache, nausea, chills, flushing, myalgia, hypotension, hypertension, chest discomfort, and fatigue. Infrequent adverse reactions include thromboembolic events, skin reactions, aseptic meningitis, renal tubular necrosis, and severe anaphylactic reaction.

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